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Welcome to the Carreira Research Group

Professor Carreira's research program focuses on the asymmetric synthesis of biologically active, stereochemically complex, natural products. Target molecules are selected which pose unique challenges in asymmetric bond construction. A complex multistep synthesis endeavor provides a goal-oriented setting within which to engage in reaction innovation and design. Drawing from the areas of organometallic chemistry, coordination chemistry, and molecular recognition, Carreira's group is developing catalytic and stoichiometric reagents for asymmetric stereocontrol.

Enlarged view: Carreira Group at ETH (June 2023)
Carreira Group at ETH  (June 2023)

Recent Publications

Check out these recent publications from the Carreira lab:

S. M. Papidocha, E. M. Carreira, J. Am. Chem. Soc. 2024, ASAP. external page Construction of Vicinal Quaternary Centers via Ru-Catalyzed Enantiospecific Allylic Substitution with Lithium Ester Enolates

H. Lindner, M. Schneider, P. Mader, F. Su, E. M. Carreira, Org. Lett. 2024, 26, 5467–5471. external page Synthesis of Primary Amines via Hydrogen Atom Transfer-Initiated Cyclization/Reduction Cascade of Unsaturated Nitriles

H. Lindner, E. M. Carreira, Angew. Chem. Int. Ed. 2024, e202407827. external page Cobalt-Catalyzed Photo-Semipinacol Rearrangement of Unactivated Allylic Alcohols

M. Fink, J. Stäuble, M. Weisgerber, E. M. Carreira, J. Am. Chem. Soc. 2024, 146, 9519–9525. external page Aryl Azocyclopropeniums: Minimalist, Visible-Light Photoswitches

M. Kosar, R. C. Sarott, D. A. Sykes, A. E. G. Viray, R. M. Vitale, N. Tomašević, X. Li, R. L. Z. Ganzoni, B. Kicin, L. Reichert, K. J. Patej, U. Gómez-Bouzó, W. Guba, P. J. McCormick, T. Hua, C. W. Gruber, D. B. Veprintsev, J. A. Frank, U. Grether, E. M. Carreira, ACS Cent. Sci. 2024, 10, 956–968. external page Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists

H. Lindner, W. M. Amberg, T. Martini, D. M. Fischer, E. Moore, E. M. Carreira, Angew. Chem. Int. Ed. 2024, e202319515. external page Photo- and Cobalt-Catalyzed Synthesis of Heterocycles via Cycloisomerization of Unactivated Olefins

You may find a complete list of recent publications here.

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