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Welcome to the Carreira Research Group

Professor Carreira's research program focuses on the asymmetric synthesis of biologically active, stereochemically complex, natural products. Target molecules are selected which pose unique challenges in asymmetric bond construction. A complex multistep synthesis endeavor provides a goal-oriented setting within which to engage in reaction innovation and design. Drawing from the areas of organometallic chemistry, coordination chemistry, and molecular recognition, Carreira's group is developing catalytic and stoichiometric reagents for asymmetric stereocontrol.

Enlarged view: Carreira Group at ETH (June 2023)
Carreira Group at ETH  (June 2023)

Recent Publications

Check out these recent publications from the Carreira lab:

M. Kosar, R. C. Sarott, D. A. Sykes, A. E. G. Viray, R. M. Vitale, N. Tomašević, X. Li, R. L. Z. Ganzoni, B. Kicin, L. Reichert, K. J. Patej, U. Gómez-Bouzó, W. Guba, P. J. McCormick, T. Hua, C. W. Gruber, D. B. Veprintsev, J. A. Frank, U. Grether, E. M. Carreira, ACS Cent. Sci. 2024, ASAP. external pageFlipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists

H. Lindner, W. M. Amberg, T. Martini, D. M. Fischer, E. Moore, E. M. Carreira, Angew. Chem. Int. Ed. 2024, e202319515. external pagePhoto- and Cobalt-Catalyzed Synthesis of Heterocycles via Cycloisomerization of Unactivated Olefins

M. Gazorpak, K. M. Hugentobler, D. Paul, P.-L. Germain, M. Kretschmer, I. Ivanova, S. Frei, K. Mathis, R. Rudolf, S. M. Barrenechea, V. Fischer, X. Xue, A. L. Ptaszek, J. Holzinger, M. Privitera, A. Hierlemann, O. C. Meijer, R. Konrat, E. M. Carreira, J. Bohacek & K. Gapp, Nat. Commun. 2023, 14, 8177. external pageHarnessing PROTAC technology to combat stress hormone receptor activation

C. Thomas, R. Erni, J. Y. Wu, F. Fischer, G. Lamers, G. Grigolon, S. J. Mitchell, K. Zarse, E. M. Carreira & M. Ristow, Nat. Commun. 2023, 14, 8142. external pageA naturally occurring polyacetylene isolated from carrots promotes health and delays signatures of aging

M. J. Classen, B. Kicin, V. A. P. Ruf, A. Hamminger, L. Ribadeau-Dumas, W. M. Amberg, E. M. Carreira, J. Am. Chem. Soc. 2023, ASAP. external pageTotal Synthesis of (+)-Euphorikanin A via an Atropospecific Cascade

H. Lindner, W. M. Amberg, E. M. Carreira, J. Am. Chem. Soc. 2023, 145, 22347–22353external pageIron-Mediated Photochemical Anti-Markovnikov Hydroazidation of Unactivated Olefins

H. H. Bulthaupt, F. Glatz, S. M. Papidocha, C. Wu, S. Teh, S. Wolfrum, L. Balážová, C. Wolfrum, E. M. Carreira, J. Am. Chem. Soc. 2023, 145, 21562–21568external pageEnantioselective Total Syntheses of Cassane Furanoditerpenoids and Their Stimulation of Cellular Respiration in Brown Adipocytes

S. M. Papidocha, H. H. Bulthaupt, E. M. Carreira, Angew. Chem. Int. Ed. 2023, e202310149. external pageSynthesis of Neocaesalpin A, AA, and Nominal Neocaesalpin K

You may find a complete list of recent publications here.

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