Chemical Biology
Synthesis of Cannabinoids and their Application in the Elucidation of Receptor Expression and Signaling Pathways:
For more information, check out the following publications:
- external pageR. C. Sarott, A. E. G. Viray, P. Pfaff, A. Sadybekov, G. Rajic, V. Katritch, E. M. Carreira, J. A. Frank, J. Am. Chem. Soc., 2021, 143, 736–743.call_made
- external pageR. C. Sarott, M. Westphal, P. Pfaff et. al, J. Am. Chem. Soc., 2020, 142, 16953–16964.call_made
- external pageM.V. Westphal, R.C. Sarott, E.A. Zirwes, A. Osterwald, W. Guba, C. Ullmer, U. Grether, E.M. Carreira, Chem. Eur. J. 2020, 26, 1380–1387.call_made
- external pageM. Soethoudt, S.C. Stolze, M.V. Westphal, L. van Stralen, A. Martella, E.J. van Rooden, W. Guba, Z.V. Varga, H. Deng, S.I. van Kasteren, U. Grether, A.P. IJzerman, P. Pacher, E.M. Carreira, H.S. Overkleeft, A. Ioan-Facsinay, L.H. Heitman, M. van der Stelt, J. Am. Chem. Soc., 2018, 140, 6067–6075.call_made
- external pageM.V. Westphal, M.A. Schafroth, R.C. Sarott, M.A. Imhof, C.P. Bold, P. Leippe, A. Dhopeshwarkar, J.M. Grandner, V. Katritch, K. Mackie, D. Trauner, E.M. Carreira, J.A. Frank, J. Am. Chem. Soc. 2017, 139, 18206–18212.call_made
Design and Synthesis of photoswitchable PROTACs (photoPROTACs) for Reversible Optical Control of Induced Protein Degradation.
For more information, check out the following publication:
Chemoproteomic tools for the identification of ligand-receptor interactions on living cells:
For more information, check out the following publications:
- external pageA.P. Frei, O-Y. Jeon, S. Kilcher, H. Moest, L.M. Henning, C. Jost, A. Plückthun, J. Mercer, R. Aebersold, E.M. Carreira, B. Wollscheid, Nat. Biotech. 2012, 30, 997–1001.call_made
- external pageN. Sobotzki, M.A. Schafroth, A. Rudnicka, A. Koetemann, F. Marty, S. Goetze, Y. Yamauchi, E.M. Carreira, B. Wollscheid, Nat. Comm. 2018, 9, 1519.call_made
Total Synthesis and SAR Studies of Prostaglandin 15d-PGJ2 and Related Isoprostanes:
For more information, check out the following publications:
- external pageH. Wolleb, S. Ogawa, M. Schneider, A. Shemet, J. Muri, M. Kopf, E.M. Carreira, Org. Lett., 2018, 20, 3014−3016.call_made
- external pageJ. Egger, S. Fischer, P. Bretscher, S. Freigang, M. Kopf, E. M. Carreira, Org. Lett. 2015, 17, 4340.call_made
- external pageP. Bretscher, J. Egger, A. Shamshiev, M. Trötzmüller, H. Köfeler, E. M. Carreira, M. Kopf, S. Freigang, EMBO Mol Med 2015, 7, 593.call_made
- external pageJ. Egger, P. Bretscher, S. Freigang, M. Kopf, E. M. Carreira, J. Am. Chem. Soc. 2014, 136, 17382.call_made
- external pageJ. Egger, P. Bretscher, S. Freigang, M. Kopf, E. M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 5382.call_made
Synthesis, Biological Evaluation and Use as a Bioprobe of Amphotericin B and its Derivatives:
For more information, check out the following publications:
- external pageA.R. Everitt, S. Clare, J.M. Perreira, G. Savidis, A.M. Aker, S.P. John, D. Sarlah, E.M. Carreira, S.J. Elledge, P. Kellam, A.L. Brass, Cell Reports 2013, 5, 895.call_made
- external pageM.P. Croatt, E.M. Carreira, Org. Lett. 2011, 13, 1390.call_made
- external pageA.A. Volmer, A.M. Szpilman, E.M. Carreira, Nat. Prod. Rep. 2010, 27, 1329.call_made
- external pageA.A. Volmer, E.M. Carreira, ChemBioChem 2010, 11, 778.call_made
- external pageA.M. Szpilman, D.M. Cereghetti, J.M. Manthorpe, N.R. Wurtz, E.M. Carreira, Chem. Eur. J. 2009, 15, 7117.call_made
- external pageA. Zumbuehl, P. Stano, M. Sohrmann, R. Dietiker, M. Peter, E.M. Carreira, ChemBioChem 2009, 10, 1617.call_made
- external pageA.M. Szpilman, J.M. Manthorpe, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4339.call_made
- external pageA.M. Szpilman, D.M. Cereghetti, N.R. Wurtz, J.M. Manthorpe, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4335.call_made
- external pageV. Paquet, A.A. Volmer, E.M. Carreira, Chem. Eur. J. 2008, 14, 2465.call_made
- external pageA. Zumbuehl, P. Stano, M. Sohrmann, M. Peter, P. Walde, E.M. Carreira, Org. Biomol. Chem. 2007, 5, 1339.call_made
- external pageV. Paquet, A. Zumbuehl, E.M. Carreira, Bioconjugate Chem. 2006, 17, 1460.call_made
- external pageD.M. Cereghetti, E.M. Carreira, Synthesis 2006, 914.call_made