Natural Product Synthesis
One of the main areas of Prof. Carreira's research is the total synthesis of structurally complex and biologically active natural products. A list of completed targets is provided.
A review published in Acc. Chem. Res. highlights recent total syntheses: external page Discovery and Surprises with Cyclizations, Cycloadditions, Fragmentations, and Rearrangements in Complex Settings
Highlights of Recent Total Syntheses:
(+)-Shearinines D and G
For more information, check out the following publications:
(+)-Euphorikanin A
For more information, check out the following publications:
(–)-Mitrephorone A
For more information, check out the following publications:
- external page M. Schneider, M. J. R. Richter, and E. M Carreira, J. Am. Chem. Soc., 2020, 142, 17802–17809.
- external page M. Schneider, M.J.R. Richter, S. Krautwald, E.M. Carreira, Org. Lett. 2019, 21, 8705-8707.
- external page M.J.R. Richter, M. Schneider, M. Brandstätter, S. Krautwald, E.M. Carreira, J. Am. Chem. Soc., 2018, 140, 16704–16710.
Chlorosulfolipids
For more information, check out the following publications:
- external page P. Sondermann, E.M. Carreira, J. Am. Chem. Soc. 2019, 141, 10510–10519.
- external page J. Boshkow, S. Fischer, A.M. Bailey, S. Wolfrum, E.M. Carreira, Chem. Sci. 2017, 8, 6904–6910.
- external page A. M. Bailey, S. Wolfrum, E.M. Carreira Angew. Chem. Int. 2016, 55, 639–643.
- external page C. Nilewski, R. W. Geisser, E.M. Carreira, Nature 2009, 547, 573.
- external page C. Nilewski, R. W. Geisser, M.-O. Ebert, J. Am. Chem. Soc. 2009, 131, 15866.
(–)-Merochlorin A
For more information, check out the following publication: