Publications 2005-2013
245
Amphotericin B Increases Influenza A Virus Infection by Preventing IFITM3-Mediated Restriction.
A.R. Everitt, S. Clare, J.M. Perreira, G. Savidis, A.M. Aker, S.P. John, D. Sarlah, E.M. Carreira, S.J. Elledge, P. Kellam, A.L. Brass, Cell Reports 2013, 5, 895.
external page http://dx.doi.org/10.1016/j.celrep.2013.10.033
244
Ir-Catalyzed Preparation of SF5-Substituted Potassium Aryl Trifluoroborates via C–H Borylation and Their Application in the Suzuki–Miyaura Reaction.
A. Joliton, E.M. Carreira, Org. Lett. 2013, 15, 5147.
external page http://dx.doi.org/10.1021/ol4025666
243
Total Synthesis of (+)-Asperolide C by Iridium-Catalyzed Enantioselective Polyene Cyclization.
O.F. Jeker, A.G. Kravina, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 12166.
external page http://dx.doi.org/10.1002/anie.201307187
242
Ring Expansion of 3-Oxetanone-Derived Spirocycles: Facile Synthesis of Saturated Nitrogen Heterocycles.
S.A. Ruider, S. Müller, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 11908.
external page http://dx.doi.org/10.1002/anie.201306563
241
Construction of Multifunctional Modules for Drug Discovery: Synthesis of Novel Thia/Oxa-Azaspiro[3.4]octanes.
D.B. Li, M. Rogers-Evans, E.M. Carreira, Org. Lett. 2013, 15, 4766.
external page http://dx.doi.org/10.1021/ol402127b
240
Total Synthesis of (+)-Crotogoudin.
S. Breitler, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 11168. (VIP Paper)
external page http://dx.doi.org/10.1002/anie.201305822
239
Synthesis and Stability of Oxetane Analogs of Thalidomide and Lenalidomide.
J. A. Burkhard, G. Wuitschik, J.-M. Plancher, M. Rogers-Evans, E.M. Carreira, Org. Lett. 2013, 15, 4312.
external page http://dx.doi.org/10.1021/ol401705a
238
Homologative Trifluoromethylation of Acetals.
J.Y. Hamilton, B. Morandi, E.M. Carreira, Synthesis 2013, 45, 1857.
external page http://dx.doi.org/10.1055/s-0033-1338485
237
Enantio- and Diastereodivergent Dual Catalysis: α-Allylation of Branched Aldehydes.
S. Krautwald, D. Sarlah, M.A. Schafroth, E.M. Carreira, Science 2013, 340, 1065.
external page http://dx.doi.org/10.1126/science.1237068
236
Total Synthesis of (±)-Gelsemoxonine.
S. Diethelm, E.M. Carreira, J. Am. Chem. Soc. 2013, 135, 8500.
external page http://dx.doi.org/10.1021/ja403823n
235
Iridium-Catalyzed Enantioselective Allylic Alkynylation.
J.Y. Hamilton, D. Sarlah, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 7532.
external page http://dx.doi.org/10.1002/anie.201302731
234
Ruthenium-Catalyzed Intramolecular Hydrocarbamoylation of Allylic Formamides: Convenient Access to Chiral Pyrrolidones.
N. Armanino, E.M. Carreira, J. Am. Chem. Soc. 2013, 135, 6814.
external page http://dx.doi.org/10.1021/ja4026787
233
On the Polarity of Partially Fluorinated Methyl Groups.
Q.A. Huchet, B. Kuhn, B. Wagner, H. Fischer, M. Kansy, D. Zimmerli, E.M. Carreira, K. Müller, J. Fluorine Chem. 2013, 152, 119.
external page http://dx.doi.org/10.1016/j.jfluchem.2013.02.023
232
Synthesis of Epoxyisoprostanes: Effects in Reducing Secretion of Pro-inflammatory Cytokines IL-6 and IL-12.
J. Egger, P. Bretscher, S. Freigang, M. Kopf, E.M. Carreira, Angew. Chem. Int. Ed. 2013, 52, 5382. (VIP Paper)
external page http://dx.doi.org/10.1002/anie.201300739
231
Photocatalytic Synthesis of Allylic Trifluoromethyl Substituted Styrene Derivatives in Batch and Flow.
L.M. Kreis, S. Krautwald, N. Pfeiffer, R.E. Martin, E.M. Carreira, Org. Lett. 2013, 15, 1634.
external page http://dx.doi.org/10.1021/ol400410m
230
Iridium-Catalyzed Enantioselective Allylic Vinylation.
J.Y. Hamilton, D. Sarlah, E.M. Carreira, J. Am. Chem. Soc. 2013, 135, 994.
external page http://dx.doi.org/10.1021/ja311422z
229
Direct Identification of Ligand-Receptor Interactions on Living Cells and Tissues.
A.P. Frei, O-Y. Jeon, S. Kilcher, H. Moest, L.M. Henning, C. Jost, A. Plückthun, J. Mercer, R. Aebersold, E.M. Carreira, B. Wollscheid, Nature Biotechnology 2012, 30, 997.
external page http://dx.doi.org/10.1038/nbt.2354
228
Iridium-Catalyzed Enantioselective Polyene Cyclization.
M.A. Schafroth, D. Sarlah, S. Krautwald, E.M. Carreira, J. Am. Chem. Soc. 2012, 134, 20276.
external page http://dx.doi.org/10.1021/ja310386m
227
Total Synthesis and Stereochemical Revision of the Chlorinated Sesquiterpene (±)-Gomerone C.
N. Huwyler, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 13066.
external page http://dx.doi.org/10.1002/anie.201207203
226
Cyclohexyne Cycloinsertion in the Divergent Synthesis of Guanacastepenes.
C.M. Gampe, E.M. Carreira, Chem. Eur. J. 2012, 18, 15761.
external page http://dx.doi.org/10.1002/chem.201202222
225
Nonlinear Effects with Diastereomeric Ligand Mixtures in Enantioselective, Catalytic Additions of Terminal Alkynes Involving Copper–PINAP Complexes.
P. Zarotti, T.F. Knöpfel, P. Aschwanden, E.M. Carreira, ACS Catal. 2012, 2, 1232.
external page http://dx.doi.org/10.1021/cs300146x
224
pH-Independent Transfer Hydrogenation in Water: Catalytic, Enantioselective Reduction of β-Keto Esters.
M.A. Ariger, E.M. Carreira, Org. Lett. 2012, 14, 4522.
external page http://dx.doi.org/10.1021/ol301903c
223
Enantioselective Allylic Thioetherification: The Effect of Phosphoric Acid Diester on Iridium-Catalyzed Enantioconvergent Transformations.
M. Roggen, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 8652.
external page http://dx.doi.org/10.1002/anie.201202092
222
Total Synthesis of Bafilomycin A1.
F. Kleinbeck, G.J. Fettes, L.D. Fader, E.M. Carreira, Chem. Eur. J. 2012, 18, 3598.
external page http://dx.doi.org/10.1002/chem.201102797
221
Iron-Catalyzed Cyclopropanation with Glycine Ethyl Ester Hydrochloride in Water.
B. Morandi, A. Dolva, E.M. Carreira, Org. Lett. 2012, 14, 2162.
external page http://dx.doi.org/10.1021/ol300688p
220
Preparation of Trifluoromethyl-Substituted Aziridines with in Situ Generated CF3CHN2.
S.A. Künzi, B. Morandi, E.M. Carreira, Org. Lett. 2012, 14, 1900.
external page http://dx.doi.org/10.1021/ol300539e
219
Iron-Catalyzed Cyclopropanation in 6 M KOH with in Situ Generation of Diazomethane.
B. Morandi, E.M. Carreira, Science 2012, 335, 1471.
external page http://dx.doi.org/10.1126/science.1218781
218
Arynes and Cyclohexyne in Natural Product Synthesis.
C.M. Gampe, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3766.
external page http://dx.doi.org/10.1002/anie.201107485
217
Recent Advances in the Total Synthesis of Chlorosulfolipids.
C. Nilewski, E.M. Carreira, Eur. J. Org. Chem. 2012, 1685.
external page http://dx.doi.org/10.1002/ejoc.201101525
216
Total Synthesis and Stereochemical Reassignment of (±)-Indoxamycin B.
O.F. Jeker, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3474.
external page http://dx.doi.org/10.1002/anie.201109175
215
Total Synthesis of (−)-Dendrobine.
L.M. Kreis, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3436.
external page http://dx.doi.org/10.1002/anie.201108564
214
Direct, Enantioselective Iridium-Catalyzed Allylic Amination of Racemic Allylic Alcohols.
M. Lafrance, M. Roggen, E.M. Carreira, Angew. Chem. Int. Ed. 2012, 51, 3470.
external page http://dx.doi.org/10.1002/anie.201108287
213
Expanding the Azaspiro[3.3]heptane Family: Synthesis of Novel Highly Functionalized Building Blocks.
J.A. Burkhard, C. Guérot, H. Knust, E.M. Carreira, Org. Lett. 2012, 14, 66.
external page http://dx.doi.org/10.1021/ol2028459
212
Expedient Preparation of Trifluoromethyl-Substituted Benzofuranols.
B. Morandi, E.M. Carreira, Org. Lett. 2011, 13, 5984.
external page http://dx.doi.org/10.1021/ol202423s
211
Synthesis of Novel Azaspiro[3.4]octanes as Multifunctional Modules in Drug Discovery.
D.B. Li, M. Rogers-Evans, E.M. Carreira, Org. Lett. 2011, 13, 6134.
external page http://dx.doi.org/10.1021/ol2025313
210
Total Synthesis of (+)-Daphmanidin E.
M.E. Weiss, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 11501. (VIP Paper)
external page http://dx.doi.org/10.1002/anie.201104681
209
Cobalt-Catalyzed Coupling of Alkyl Iodides with Alkenes: Deprotonation of Hydridocobalt Enables Turnover.
M.E. Weiss, L.M. Kreis, A. Lauber, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 11125.
external page http://dx.doi.org/10.1002/anie.201105235
208
Towards the Synthesis of Massadine: A Unified Strategy for the Stereoselective Synthesis of the Carbocyclic C,D-Ring Subunit.
A. Breder, G.M. Chinigo, A.W. Waltman, E.M. Carreira, Chem. Eur. J. 2011, 17, 12405.
external page http://dx.doi.org/10.1002/chem.201101862
207
Catalytic Asymmetric Intramolecular Hydroacylation with Rhodium/Phosphoramidite–Alkene Ligand Complexes.
T.J. Hoffman, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 10670.
external page http://dx.doi.org/10.1002/anie.201104595
206
One-Pot Synthesis of Novel Photochromic Oxazine Compounds.
W. Zhao, E.M. Carreira, Org. Lett. 2011, 13, 5048.
external page http://dx.doi.org/10.1021/ol2019482
205
Synthesis of Trifluoroethyl-Substituted Ketones from Aldehydes and Cyclohexanones
B. Morandi, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 9085.
external page http://dx.doi.org/10.1002/anie.201103526
204
Iridium Diamine Catalyst for the Asymmetric Transfer Hydrogenation of Ketones.
H. Vázquez-Villa, S. Reber, M.A. Ariger, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 8979.
external page http://dx.doi.org/10.1002/anie.201102732
203
Synthesis of Undecachlorosulfolipid A: Re-evaluation of the Nominal Structure.
C. Nilewski, N.R. Deprez, T.C. Fessard, D.B. Li, R.W. Geisser, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 7940. (VIP paper)
external page http://dx.doi.org/10.1002/anie.201102521
202
Iron-Catalyzed Preparation of Trifluoromethyl Substituted Vinyl- and Alkynylcyclopropanes.
B. Morandi, J. Cheang, E.M. Carreira, Org. Lett. 2011, 13, 3080.
external page http://dx.doi.org/10.1021/ol200983s
201
Enantioselective Allylic Etherification: Selective Coupling of Two Unactivated Alcohols.
M. Roggen, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 5568.
external page http://dx.doi.org/10.1002/anie.201007716
200
Cascade Formation of Isoxazoles: Facile Base-Mediated Rearrangement of Substituted Oxetanes.
J.A. Burkhard, B.H. Tchitchanov, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 5379. (hot paper)
external page http://dx.doi.org/10.1002/anie.201100260
199
Total Syntheses of Guanacastepenes N and O.
C.M. Gampe, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 2962.
external page http://dx.doi.org/10.1002/anie.201007644
198
Asymmetric Autocatalysis Enables an Improved Synthesis of Efavirenz.
N. Chinkov, A. Warm, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 2957.
external page http://dx.doi.org/10.1002/anie.201006689
197
Probing the Role of the Mycosamine C2'-OH on the Activity of Amphotericin B.
M.P. Croatt, E.M. Carreira, Org. Lett. 2011, 13, 1390.
external page http://dx.doi.org/10.1021/ol2000765
196
Synthesis of Novel Angular Spirocyclic Azetidines.
C. Guérot, B.H. Tchitchanov, H. Knust, E.M. Carreira, Org. Lett. 2011, 13, 780.
external page http://dx.doi.org/10.1021/ol103050c
195
Enantioselective Cobalt-Catalyzed Preparation of Trifluoromethyl-Substituted Cyclopropanes.
B. Morandi, B. Mariampillai, E.M. Carreira, Angew. Chem. Int. Ed. 2011, 50, 1101.
external page http://dx.doi.org/10.1002/anie.201004269
194
Ugi-4-Component Reaction Enabling Rapid Access to the Core Fragment of Massadine.
G.M. Chinigo, A. Breder, E.M. Carreira, Org. Lett. 2011, 13, 78.
external page http://dx.doi.org/10.1021/ol102577q
193
Probing the Biology of Natural Products: Molecular Editing by Diverted Total Synthesis.
A.M. Szpilman, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 9592.
external page http://dx.doi.org/10.1002/anie.200904761
192
Oxetanes as Versatile Elements in Drug Discovery and Synthesis.
J.A. Burkhard, G. Wuitschik, M. Rogers-Evans, K. Müller, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 9052.
external page http://dx.doi.org/10.1002/anie.200907155
191
Total Synthesis of Nominal Banyaside B: Structural Revision of the Glycosylation Site.
C.S. Schindler, L. Bertschi, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 9229.
external page http://dx.doi.org/10.1002/anie.201004047
190
Cycloaddition Reactions
A.M. Szpilman, E.M. Carreira. In Silver in Organic Chemistry; M. Harmata, Ed.; John Wiley & Sons, Inc.: Hoboken, New Jersey, 2010; pp 43–82.
external page http://doi.org/10.1002/9780470597521.ch2
189
Facile Formation of N-Acyl-oxazolidinone Derivatives Using Acid Fluorides.
C.S. Schindler, P.M. Forster, E.M. Carreira, Org. Lett. 2010, 12, 4102.
external page http://dx.doi.org/10.1021/ol1016977
188
Synthesis of Microcin SF608 through Nucleophilic Opening of an Oxabicyclo[2.2.1]heptane.
S. Diethelm, C.S. Schindler, E.M. Carreira, Org. Lett. 2010, 12, 3950.
external page http://dx.doi.org/10.1021/ol1017189
187
Stereospecific Substitution of Allylic Alcohols To Give Optically Active Primary Allylic Amines: Unique Reactivity of a (P,alkene)Ir Complex Modulated by Iodide.
M. Roggen, E.M. Carreira, J. Am. Chem. Soc. 2010, 132, 11917.
external page http://dx.doi.org/10.1021/ja105271z
186
Synthesis and Biological Evaluation of Amphotericin B Derivatives.
A.A. Volmer, A.M. Szpilman, E.M. Carreira, Nat. Prod. Rep. 2010, 27, 1329.
external page http://dx.doi.org/10.1039/b820743g
185
Transfer Hydrogenation in Water: Enantioselective, Catalytic Reduction of α-Cyano and α-Nitro Substituted Acetophenones.
O. Soltani, M.A. Ariger, H. Vázquez-Villa, E.M. Carreira, Org. Lett. 2010, 12, 2893.
external page http://dx.doi.org/10.1021/ol1008894
184
Rhodium-Catalyzed Cyclopropenation of Alkynes: Synthesis of Trifluoromethyl-Substituted Cyclopropenes.
B. Morandi, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 4294.
external page http://dx.doi.org/10.1002/anie.201000787
183
Cyclohexyne Cycloinsertion by an Annulative Ring Expansion Cascade.
C.M. Gampe, S. Boulos, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 4092.
external page http://dx.doi.org/10.1002/anie.201001137
182
Synthesis of Azaspirocycles and their Evaluation in Drug Discovery.
J.A. Burkhard, B. Wagner, H. Fischer, F. Schuler, K. Müller, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 3524.
external page http://dx.doi.org/10.1002/anie.200907108
181
Synthesis and Structural Analysis of a New Class of Azaspiro[3.3]heptanes as Building Blocks for Medicinal Chemistry.
J.A. Burkhard, C. Guérot, H. Knust, M. Rogers-Evans, E.M. Carreira, Org. Lett. 2010, 12, 1944.
external page http://dx.doi.org/10.1021/ol1003302
180
Oxetanes in Drug Discovery: Structural and Synthetic Insights.
G. Wuitschik, E.M. Carreira, B. Wagner, H. Fischer, I. Parrilla, F. Schuler, M. Rogers-Evans, K. Müller, J. Med. Chem. 2010, 53, 3227.
external page http://dx.doi.org/10.1021/jm9018788
179
Differential Interaction of an AmB Analogue and Ergosterol in Enantiomeric Membranes.
O.-Y. Jeon, E.M. Carreira, Org. Lett. 2010, 12, 1772.
external page http://dx.doi.org/10.1021/ol1003516
178
Active Amphotericin B Derivatives Position the Mycosamine in Two Radial Orientations.
A.A. Volmer, E.M. Carreira, ChemBioChem 2010, 11, 778.
external page http://dx.doi.org/10.1002/cbic.201000080
177
Iron-Catalyzed Cyclopropanation with Trifluoroethylamine Hydrochloride and Olefins in Aqueous Media: In Situ Generation of Trifluoromethyl Diazomethane.
B. Morandi, E.M. Carreira, Angew. Chem. Int. Ed. 2010, 49, 938.
external page http://dx.doi.org/10.1002/anie.200905573
176
Synthesis of (3-Chlorobutyl)benzene by the Cobalt-Catalyzed Hydrochlorination of 4-Phenyl-1-butene.
B. Gaspar, J. Waser, E.M. Carreira, Org. Syn. 2010, 87, 88.
external page http://www.orgsyn.org/orgsyn/prep.asp?prep=v87p0088
175
Stereoselective Synthesis of Erythronolide A via Nitrile Oxide Cycloadditions and Related Studies.
D. Muri, E.M. Carreira, J. Org. Chem. 2009, 74, 8695.
external page http://dx.doi.org/10.1021/jo901817b
174
Conformational and Configurational Analysis in the Study and Synthesis of Chlorinated Natural Products.
C. Nilewski, R.W. Geisser, M.-O. Ebert, E.M. Carreira, J. Am. Chem. Soc. 2009, 131, 15866.
external page http://dx.doi.org/10.1021/ja906461h
173
Rapid formation of complexity in the total synthesis of natural products enabled by oxabicyclo[2.2.1]heptene building blocks.
C.S. Schindler, E.M. Carreira, Chem. Soc. Rev. 2009, 38, 3222.
external page http://dx.doi.org/10.1039/b915448p
172
Polyketide Building Blocks via Diastereoselective Nitrile Oxide Cycloadditions with Homoallylic Alcohols and Monoprotected Homoallylic Diols.
N. Lohse-Fraefel, E.M. Carreira, Chem. Eur. J. 2009, 15, 12065.
external page http://dx.doi.org/10.1002/chem.200900529
171
Cobalt Catalyzed Functionalization of Unactivated Alkenes: Regioselective Reductive C−C Bond Forming Reactions.
B. Gaspar, E.M. Carreira, J. Am. Chem. Soc. 2009, 131, 13214.
external page http://dx.doi.org/10.1021/ja904856k
170
Transfer Hydrogenation in Water: Enantioselective, Catalytic Reduction of (E)-β,β-Disubstituted Nitroalkenes.
O. Soltani, M.A. Ariger, E.M. Carreira, Org. Lett. 2009, 11, 4196.
external page http://dx.doi.org/10.1021/ol901332e
169
Nucleophilic Opening of Oxabicyclic Ring Systems.
C.S. Schindler, S. Diethelm, E.M. Carreira, Angew. Chem. Int. Ed. 2009, 48, 6296.
external page http://dx.doi.org/10.1002/anie.200902046
168
Structure determination of slowly Exchanging Conformers in Solution Using High-Resolution NMR, Computational Modeling and DFT-GIAO Chemical Shielding: Application to an Erythronolide A derivative.
D. Muri, C. Corminboeuf, E.M. Carreira, D. Jeannerat, Magn. Reson. Chem. 2009, 47, 909.
external page http://dx.doi.org/10.1002/mrc.2476
167
Catalytic Decarbonylation of Epoxyaldehydes: Applications to the Preparation of Terminal Epoxides.
B. Morandi, E.M. Carreira, Synlett 2009, 2076.
external page http://dx.doi.org/10.1055/s-0029-1217562
166
Synthesis and Biophysical Studies on 35-Deoxy Amphotericin B Methyl Ester.
A.M. Szpilman, D.M. Cereghetti, J.M. Manthorpe, N.R. Wurtz, E.M. Carreira, Chem. Eur. J. 2009, 15, 7117.
external page http://dx.doi.org/10.1002/chem.200900231
165
Synthesis and Investigation of Tryptophan-Amphotericin B Conjugates.
A. Zumbuehl, P. Stano, M. Sohrmann, R. Dietiker, M. Peter, E.M. Carreira, ChemBioChem 2009, 10, 1617.
external page http://dx.doi.org/10.1002/cbic.200900096
164
β-Glycosidation of Sterically Hindered Alcohols.
A.M. Szpilman, E.M. Carreira, Org. Lett. 2009, 11, 1305.
external page http://dx.doi.org/10.1021/ol9000735
163
Total Synthesis of a Chlorosulpholipid Cytotoxin Associated with Seafood Poisoning.
C. Nilewski, R.W. Geisser, E.M. Carreira, Nature 2009, 547, 573.
external page http://dx.doi.org/10.1038/nature07734
162
E.M. Carreira and L. Kværnø, Classics in Stereoselective Synthesis, Wiley: Weinheim, 2009.
161
Total Synthesis of Bafilomycin A1.
F. Kleinbeck, E.M. Carreira, Angew. Chem. Int. Ed. 2009, 48, 578.
external page http://dx.doi.org/10.1002/anie.200804645
160
Enantioselective Synthesis of the Core of Banyaside, Suomilide, and Spumigin HKVV.
C.S. Schindler, C.R.J. Stephenson, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 8852.
external page http://dx.doi.org/10.1002/anie.200803655
159
Enantioselective Synthesis of the Carbocyclic D-Ring Subunit of Massadine.
A. Breder, G.M. Chinigo, A.W. Waltman, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 8514.
external page http://dx.doi.org/10.1002/anie.200803284
158
Unraveling a Molecular Target of Macrolides.
K.-H. Altmann, E.M. Carreira, Nat. Chem. Biol. 2008, 4, 388.
external page http://dx.doi.org/10.1038/nchembio0708-388
157
2,6-Diazaspiro[3.3]heptanes: Synthesis and Application in Pd-Catalyzed Aryl Amination Reactions.
J. Burkhard, E.M. Carreira, Org. Lett. 2008, 10, 3525.
external page http://dx.doi.org/10.1021/ol801293f
156
Catalytic Hydrochlorination of Unactivated Olefins with para-Toluenesulfonyl Chloride.
B. Gaspar, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 5758.
external page http://dx.doi.org/10.1002/ange.200801760
155
Spirocyclic Oxetanes: Synthesis and Properties.
G. Wuitschik, M. Rogers-Evans, A. Buckl, M. Bernasconi, M. Märki, T. Godel, H. Fischer, B. Wagner, I. Parrilla, F. Schuler, J. Schneider, A. Alker, W.B. Schweizer, K. Müller, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4512.
external page http://dx.doi.org/10.1002/anie.200800450
154
Synthesis and Biological Studies of 35-Deoxy-Amphotericin B Methyl Ester.
A.M. Szpilman, J.M. Manthorpe, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4339.
external page http://dx.doi.org/10.1002/anie.200800590
153
Synthesis of 35-Deoxy Amphotericin B Methylester: A Strategy for Molecular Editing.
A.M. Szpilman, D.M. Cereghetti, N.R. Wurtz, J.M. Manthorpe, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4335.
external page http://dx.doi.org/10.1002/anie.200800589
152
Azides by Olefin Hydroazidation Reactions
J. Waser, E.M. Carreira. In Organic Azides: Syntheses and Applications; S. Bräse, K. Banert, Eds.; Wiley-VCH: Weinheim, 2010; pp 95–111.
external page http://doi.org/10.1002/9780470682517.ch4
151
Modern Arylations of Carbonyl Compounds
C. Defieber, E.M. Carreira. In Modern Arylation Methods; L. Ackerman, Ed.; Wiley-VCH: Weinheim, 2009; pp 271–310.
external page http://doi.org/10.1002/9783527627325
150
Chiral Olefins as Steering Ligands in Asymmetric Catalysis.
C. Defieber, H. Grützmacher, E.M. Carreira, Angew. Chem. Int. Ed. 2008, 47, 4482.
external page http://dx.doi.org/10.1002/anie.200703612
149
Synthesis and In Vitro Biological Properties of Novel Cationic Derivatives of Amphotericin B.
V. Paquet, A.A. Volmer, E.M. Carreira, Chem. Eur. J. 2008, 14, 2465.
external page http://dx.doi.org/10.1002/chem.200701237
148
Cobalt-Catalyzed Synthesis of Tertiary Azides from α,α-Disubstituted Olefins under Mild Conditions Using Commercially Available Reagents.
B. Gaspar, J. Waser, E.M. Carreira, Synthesis 2007, 3839.
external page http://dx.doi.org/10.1055/s-2007-1000817
147
Enantioselective Preparation of 1,1-Diarylethanes: Aldehydes as Removable Steering Groups for Asymmetric Synthesis.
T.C. Fessard, S.P. Andrews, H. Motoyoshi, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 9331.
external page http://dx.doi.org/10.1002/anie.200702995
146
Hydroxyl-Directed Nitrile Oxide Cycloaddition Reactions with Cyclic Allylic Alcohols.
N. Becker, E.M. Carreira, Org. Lett. 2007, 9, 3857.
external page http://dx.doi.org/10.1021/ol7017032
145
Stereoselective Conjugate Addition Reactions Using In Situ Metallated Terminal Alkynes and the Development of Novel Chiral P,N-Ligands.
S. Fujimori, E.M. Carreira, Bull. Chem. Soc. Jpn. 2007, 80, 1635.
external page http://dx.doi.org/10.1246/bcsj.80.1635
144
Cu(I)-catalyzed conjugate addition of ethyl propiolate.
S. Fujimori, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 4967.
external page http://dx.doi.org/10.1002/anie.200701098
143
Enantioselective Reduction of Nitroalkene Mixtures by in situ Equilibration.
C. Czekelius, E.M. Carreira, Org. Process Res. Dev. 2007, 11, 633.
external page http://dx.doi.org/10.1021/op700029m
142
Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane.
M. Knöpfel, J.P. Davies, P.T. Duong, L. Kværnø, E.M. Carreira, M.C. Phillips, Y.A. Ioannou, H. Hauser, Biochim. Biophys. Acta 2007, 1771, 1140.
external page http://dx.doi.org/10.1016/j.bbalip.2007.05.011
141
Mild Cobalt-Catalyzed Hydrocyanation of Olefins with Tosyl Cyanide.
B. Gaspar, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 4519.
external page http://dx.doi.org/10.1002/anie.200700575
140
Iridium-Catalyzed Synthesis of Primary Allylic Amines from Allylic Alcohols: Sulfamic Acid as Ammonia Equivalent.
C. Defieber, M.A. Ariger, P. Moriel, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 3139.
external page http://dx.doi.org/10.1002/anie.200700159
139
Pd-Catalyzed Cleavage of Benzylic Nitro Bonds: New Opportunities for Asymmetric Synthesis.
T.C. Fessard, H. Motoyoshi, E.M. Carreira, Angew. Chem. Int. Ed. 2007, 46, 2078.
external page http://dx.doi.org/10.1002/anie.200604263
138
Oligothiophene-Linked Bisnaphthopyrans: Sequential and Temperature-Dependent Photochromism.
W.L. Zhao, E.M. Carreira, Chem. Eur. J. 2007, 13, 2671.
external page http://dx.doi.org/10.1002/chem.200600958
137
A Novel Strategy for Bioconjugation: Synthesis and Preliminary Evaluation with Amphotericin B.
A. Zumbuehl, P. Stano, M. Sohrmann, M. Peter, P. Walde, E.M. Carreira, Org. Biomol. Chem. 2007, 5, 1339.
external page http://dx.doi.org/10.1039/b701953j
136
Biologically Active Amphotericin B-calix[4] arene conjugates.
V. Paquet, A. Zumbuehl, E.M. Carreira, Bioconjugate Chem. 2006, 17, 1460.
external page http://dx.doi.org/10.1021/bc060205i
135
Iridium-Catalyzed Enantioselective Synthesis of Allylic Alcohols: Silanolates as Hydroxide Equivalents.
I. Lyothier, C. Defieber, E.M. Carreira, Angew. Chem. Int. Ed. 2006, 45, 6204.
external page http://dx.doi.org/10.1002/anie.200602408
134
Oxetanes as Promising Modules in Drug Discovery.
G. Wuitschik, M. Rogers-Evans, K. Muller, H. Fischer, B. Wagner, F. Schuler, L. Polonchuk, E.M. Carreira, Angew. Chem. Int. Ed. 2006, 45, 7736.
external page http://dx.doi.org/10.1002/anie.200602343
133
Highly Enantioselective Access to Primary Propargylamines: 4-piperidinone as a Convenient Protecting Group.
P. Aschwanden, C.R.J. Stephenson, E.M. Carreira, Org. Lett. 2006, 8, 2437.
external page http://dx.doi.org/10.1021/ol060876w
132
Hydrazines and Azides via the Metal-Catalyzed Hydrohydrazination and Hydroazidation of olefins.
J. Waser, B. Gaspar, H. Nambu, E.M. Carreira, J. Am. Chem. Soc. 2006, 128, 11693.
external page http://dx.doi.org/10.1021/ja062355+
131
Amphotericin B: 50 Years of Chemistry and Biochemistry.
D.M. Cereghetti, E.M. Carreira, Synthesis 2006, 914.
external page http://dx.doi.org/10.1055/s-2006-926368
130
Significant Improvement of Antifungal Activity of Polyene Macrolides by Bisalkylation of the Mycosamine.
V. Paquet, E.M. Carreira, Org. Lett. 2006, 8, 1807.
external page http://dx.doi.org/10.1021/ol060353o
129
Synthesis and Photochromism of Novel Phenylene-Linked Photochromic Bispyrans.
W. Zhao, E.M. Carreira, Org. Lett. 2006, 8, 99.
external page http://dx.doi.org/10.1021/ol052587y
128
Synthesis of (+/-)-Strychnofoline via a Highly Convergent Selective Annulation Reaction.
A. Lerchner, E.M. Carreira, Chem. Eur. J. 2006, 12, 8209.
external page http://dx.doi.org/10.1002/chem.200600957
127
Conformationally Restricted Aza-BODIPY: Highly Fluorescent, Stable Near-Infrared Absorbing Dyes.
W.L. Zhao, E.M. Carreira, Chem. Eur. J. 2006, 12, 7254.
external page http://dx.doi.org/10.1002/chem.200600527
126
Reduction of 2,3-Dihydroisoxazoles to beta-Amino Ketones and beta-Amino Alcohols.
P. Aschwanden, L. Kværnø, R.W. Geisser, F. Kleinbeck, E.M. Carreira, Org. Lett. 2005, 25, 5741.
external page http://dx.doi.org/10.1021/ol052540c
125
Scalable Synthesis of a Mycosamine donor. Overcoming Difficult Reactivity in Allose Systems.
J.M. Manthorpe, A.M. Szpilman, E.M. Carreira, Synthesis 2005, 3380.
external page http://dx.doi.org/10.1055/s-2005-918474
124
ZnCl2-Mediated Stereoselective Addition of Terminal Alkynes to D-(+)-Mannofuranosyl Nitrones.
D. Topić, P. Aschwanden, R. Fässler, E.M. Carreira, Org. Lett. 2005, 7, 5329.
external page http://dx.doi.org/10.1021/ol052331s
123
Cobalt-Catalyzed Hydrohydrazination of Dienes and Enynes: Access to Allylic and Propargylic Hydrazides.
J. Waser, J.C. González-Gómez, H. Nambu, P. Huber, E.M. Carreira, Org. Lett. 2005, 7, 4249.
external page http://dx.doi.org/10.1021/ol0517473
122
Heterocyclic Ring Scaffolds as Small-Molecule Cholesterol Absorption Inhibitors.
T. Ritter, L. Kværnø, M. Werder, H. Hauser, E.M. Carreira, Org. Biomol. Chem. 2005, 19, 3514.
external page http://dx.doi.org/10.1039/b510100j
121
Catalytic Asymmetric Synthesis with Rh-Diene Complexes: 1,4-Addition of Arylboronic Acids to Unsaturated Esters.
J.-F. Paquin, C.R.J. Stephenson, C. Defieber, E.M. Carreira, Org. Lett. 2005, 7, 3821.
external page http://dx.doi.org/10.1021/ol051533l
120
Asymmetric Synthesis of 3,3-Diarylpropanals with Chiral Diene-Rhodium Catalysts.
J.-F. Paquin, C. Defieber, C.R.J. Stephenson, E.M. Carreira, J. Am. Chem. Soc. 2005, 127, 10850.
external page http://dx.doi.org/10.1021/ja053270w
119
Catalytic, Enantioselective, Conjugate Alkyne Addition.
T. Knöpfel, P. Zarotti, Y. Takashi, E.M. Carreira, J. Am. Chem. Soc. 2005, 127, 9682.
external page http://dx.doi.org/10.1021/ja052411r
118
Cobalt-Catalyzed Hydroazidation of Olefins: Convenient Access to Alkyl Azides.
J. Waser, H. Nambu, E.M. Carreira, J. Am. Chem. Soc. 2005, 127, 8294.
external page http://dx.doi.org/10.1021/ja052164r
117
Synthesis and In Vitro Evaluation of Inhibitors of Intestinal Cholesterol Absorption.
L. Kværnø, M. Werder, H. Hauser, E.M. Carreira, J. Med. Chem. 2005, 48, 6035.
external page http://dx.doi.org/10.1021/jm050422p
116
Total Synthesis of (–)-Spirotryprostatin B – Synthesis and Related Studies.
C. Marti, E.M. Carreira, J. Am. Chem. Soc. 2005, 127, 11505.
external page http://dx.doi.org/10.1021/ja0518880
115
A Modular Approach to Polyketide Building Blocks: Cycloadditions of Nitrile Oxides and Homoallylic Alcohols.
N. Lohse-Fraefel, E.M. Carreira, Org. Lett. 2005, 7, 2011.
external page http://dx.doi.org/10.1021/ol0504953
114
Solid Phase Synthesis of Photochromic Spiropyrans.
W. Zhao, E.M. Carreira, Org. Lett. 2005, 7, 1609.
external page http://dx.doi.org/10.1021/ol050302b
113
Carbohydrate Sulfonyl Chlorides for the Simple, Convenient Access to Glycoconjugates.
L. Kværnø, M. Werder, H. Hauser, E.M. Carreira, Org. Lett. 2005, 7, 1145.
external page http://dx.doi.org/10.1021/ol0502127
112
Total Synthesis of Erythronolide A via Mg(II)-Mediated Nitrile Oxide Cycloaddition.
D. Muri, N. Lohse, E.M. Carreira, Angew. Chem. Int. Ed. 2005, 44, 4036.
external page http://dx.doi.org/10.1002/anie.200500172
111
Convenient Transformation of Optically Active Nitroalkanes into Chiral Aldoximes and Nitriles.
C. Czekelius, E.M. Carreira, Angew. Chem. Int. Ed. 2005, 44, 612.
external page http://dx.doi.org/10.1002/anie.200461879
110
Conformationally Restricted Aza-BODIPY: A Highly Fluorescent, Stable Near-Infrared Absorbing Dye.
W. Zhao, E.M. Carreira, Angew. Chem. Int. Ed. 2005, 44, 1677.
external page http://dx.doi.org/10.1002/anie.200461868